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Careers

Advanced Cell Technology (ACT) is a world leader in the field of stem cells and regenerative medicine and is currently conducting two Phase 1/2 clinical trials using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells to treat blindness in the United States and Europe. ACT is a dynamic research company that empowers some of the most creative and talented minds in biotechnology. Our state of the art Marlborough, Massachusetts facility and dedication to our employees creates an environment of excitement and growth. We are seeking a highly motivated and intellectually Research Associate to join our research team.

Current Openings:

Senior Clinical Research Associate / Clinical Project Manager

Join an enthusiastic team in a growing cell therapy company. Advanced Cell Technology seeks a motivated, self reliant and team-oriented individual who will be a key contributor to the overall success of Advanced Cell Technologies clinical development program. The Sr. Clinical Research Associate / Clinical Project Manager will be responsible for a broad scope of varying activities to support department and corporate goals. Primary responsibilities for this position are to:

  • Plan and implement early-phase clinical research studies within budget and on schedule
  • Coordinate and lead study team meetings and update the Development Team on timelines and progress toward milestones.
  • Coordinate activities of vendors and investigators to ensure compliance with the study protocol and overall clinical objectives.
  • Contribute to the development of study documentation including protocol review, creating study manuals, and designing CRFs.
  • Ensure that study documentation is maintained according to applicable regulations, industry accepted standards, and SOPs that govern clinical studies both in the field and in-house.
  • Participate in study site selection; review and update site specific consent forms; track patient accrual and study progress via standard reports; assure patient eligibility; document protocol deviations/violations; and manage adverse event reporting.
  • Oversee clinical monitoring from site qualification to site closure visits and assure integrity of clinical data with respect to accuracy, accountability and documentation through review of case report forms, source documents, and medical records. Evaluate and analyze clinical data.
  • Provide input to Clinical Study Reports and Investigator Brochures, including data cleaning, listing review, and report writing.
  • Develop standard operating procedures (SOPs), work instructions (WIs), and standardized forms to define Clinical Department processes within a small but growing team.
  • Collaborate with Clinical, Regulatory, and Quality team members to ensure compliance of department/study activities with FDA regulations, guidelines, and principles of ICH GCP and ACT SOPs.
  • Review and negotiate contracts.
  • Limited travel possible to field sites to supervise and/or monitor clinical studies (25%).
Qualifications:

Qualified candidates will have strong oral and written communication skills with monitoring, study management, and SOP-development experience. The ideal candidate will be highly adaptable, proactive, deadline- and detail-oriented, and will maintain a high level of professional expertise through recent industry training and familiarity with clinical research publications. The candidate must be able to work independently in accomplishing assigned tasks by effective planning, communication, execution, and maintenance of cutting-edge knowledge of assigned therapeutic area by reviewing scientific and medical literature, industry news, and other sources. Biologics and Ophthalmology experience a plus.

Quality (GCP) and/or Data Management, MS Project experience is a plus. The candidate will work independently under general direction in a fast-paced environment.

Preferred Education/Experience: BS 4-8; MS 2-6.

Contact: Careers@advancedcell.com.


Advanced Cell Technology (ACT) is a world leader in the field of stem cells and regenerative medicine and is currently conducting two Phase 1/2 clinical trials using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells to treat blindness in the United States and Europe. ACT is a dynamic research company that empowers some of the most creative and talented minds in biotechnology. Our state of the art Marlborough, Massachusetts facility and dedication to our employees creates an environment of excitement and growth. We are seeking several highly motivated, independent, and intellectually curious scientists to join our research team.

Scientist/Senior Scientist in Mesenchymal Stem Cell Research

Special requirements:

The focus of ACT’s mesenchymal stem cell (MSC) program is to explore and develop the therapeutic utility of pluripotent stem cell-derived MSCs in treating a wide spectrum of disorders. We are looking for a scientist/senior scientist who has a PhD degree with 0-5 years of post-doctoral experience. The candidate should have direct working experiences in MSCs and a strong background in immunology with particular emphasis on the molecular and cellular basis of autoimmune disorders. He/she will be working closely with a small group of scientists to develop pre-clinical models for testing MSC therapeutic utility. The candidate will also take part in evaluating MSC immunosuppressive functionality and mechanisms on a cellular/molecular level. Only those candidates who are legally authorized to work in the United States will be considered.

ACT offers a competitive salary, stock options, and an excellent benefits package including health and dental insurance, 401K, and more.

To Apply:

Please, email resume with detailed description of research background and technical skills that meet the requirements, and a list of publications to: Careers@advancedcell.com.

We are an Equal Opportunity Employer.