- Fast-acting bronchodilator
- Used as a part of combined therapy
- Convenient to use
What is Atrovent?
Atrovent is a bronchodilator. It blocks m-cholinergic receptors of smooth muscles of the tracheobronchial tree and suppresses reflex bronchoconstriction. Structurally similar to the acetylcholine molecule, it is a competitive antagonist.
Anticholinergics prevent an increase in the intracellular concentration of calcium ions, which occurs due to the interaction of acetylcholine with muscarinic receptors located in the bronchial smooth muscles.
How does Atrovent work?
When inhaled, it practically does not have a resorptive effect. Bronchodilation that occurs after inhalation of Atrovent is mainly the result of local and specific effects of the drug on the lungs, and not the result of its systemic influence. Ipratropium bromide has no negative effect on mucus secretion in the respiratory tract, mucociliary clearance and gas exchange.
In controlled 85-90-day studies carried out in patients with bronchospasm caused by COPD, chronic bronchitis and pulmonary emphysema, a significant improvement in lung function was observed within 15 minutes, reached a maximum after 1-2 hours and lasted up to 4-6 hours.
How to use this inhaler?
The recommended drug dose should be diluted with 0.9% sodium chloride solution until the volume of the drug reaches 3-4 ml, filled into a nebulizer and inhaled. The drug should be diluted with 0.9% sodium chloride solution each time immediately before use. The solution remaining after inhalation is emptied out.
Dosage may depend on the inhalation method and the type of nebulizer. The duration of inhalation can be controlled by the consumption of the diluted volume.
This asthma drug can be applied using a variety of commercially available nebulizers. When using a centralized oxygen system, the solution is best used at a flow rate of 6-8 l / min.
What is Atrovent inhaler used for?
This inhaler is used for asthma control and prevention. The second diagnosis treated is COPD (chronic obstrustive pilmonary disease).
Where can I buy Atrovent?
It is possible to buy this inhaler from Advanced Cell online. The ordering procedure is simple. Find this inhaler in the list of avaiable positions. Add it to the shopping cart, fill out mandatory personal data, and then submit an order. The payment is conducted online and the order will be delivered within the stated periods of time.
When not to use Atrovent?
This inhaler cannot be used in the following cases:
- hypersensitivity to atropine and its derivatives;
- hypersensitivity to ipratropium bromide and other components of the drug.
Take the drug with caution in the following cases: angle-closure glaucoma, urinary tract obstruction, prostatic hyperplasia, during breastfeeding, children under 6 years of age.
What kind of drug is Atrovent?
Ipratropium belongs to the class of medications called bronchodilators. It works by relaxing and opening the air passages to the lungs to make breathing . easier. It is a fast-acting drug that brings fast relief over an asthma attack.
What are the side effects?
There are the following side effects:
The immune system: infrequently – hypersensitivity, anaphylactic reactions, angioedema; rarely – urticaria.
The nervous system: often – headache, dizziness.
The side of the organ of vision: infrequently – blurred vision, mydriasis, increased intraocular pressure, glaucoma, eye pain, the appearance of a halo around objects, conjunctival hyperemia, corneal edema; rarely – violation of accommodation.
The cardiovascular system: infrequently – palpitations, supraventricular tachycardia; rarely – atrial fibrillation, increased heart rate.
The respiratory system: often – irritation of the pharyngeal mucosa, cough; infrequently – bronchospasm, paradoxical bronchospasm, laryngospasm, pharyngeal edema, dryness of the pharynx.
The digestive system: often – dry mouth, nausea, impaired gastrointestinal motility; infrequently – diarrhea, constipation, vomiting, stomatitis, swelling of the oral mucosa.
The urinary system: infrequently – urinary retention.
Skin and subcutaneous tissue disorders: infrequently – rash, itching.
How long does it take for Atrovent to start working?
A significant improvement in lung function was found within 15 minutes, reached a maximum after 1-2 hours and lasted up to 4-6 hours. This effect depends on the severity of asthma and COPD.
Does it help cough?
If the coughing pathogen is not bacterial sinusitis or Bordetella pertussis, treatment with inhaled ipratropium (Atrovent) should be applied. But only a healthcare provider should prescribed this inhaler to treat cough. If the cough persists, consider with your doctor the use of inhaled corticosteroids.
Does it dry up mucus?
As it is, Atrovent doesn’t dry up mucus. It is prescribed to reduce the number of sputuum secretions. Ipratropium belongs to anticholinergics. It performs by decreasing the amount of mucus produced.
When should you use this inhaler?
This inhaler can be used when you suffer from asthma and COPD. After the doctor’s examination, a patient will be prescribed this inhaler or not. Only doctor may assess the patient’s condition.
Is Atrovent the same as Ventolin?
The effectiveness of Ipratropium is quite similar to Ventolin – this means that the ability of the drug to have the maximum possible effect is similar.
For example, if the therapeutic effect of Atrovent is more pronounced, then when using Ventolin, even in large doses, it will not be possible to achieve this effect.
An indicator of the speed of therapeutic action in Atrovent and Ventolin is approximately the same. Bioavailability, that is, the amount of a medicinal substance reaching the site of its action in the body, is similar. The higher the bioavailability, the less its losses will be during assimilation and use by the body.
The drug safety includes many factors. At the same time, the described drug has it quite similar to Ventolin. It is important where the drug is metabolized: medicinal substances are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often it involves major organs such as the liver, kidneys, lungs, skin, brain, and others. When assessing metabolism in the described inhaler, as well as in Ventolin, we look at which organ is metabolizing and how critical is the effect on it.
The risk-to-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observation of caution in use. At the same time, Ipratropium has no risks when used, as well as Ventolin.
Also, when considering safety, it is taken into account whether only allergic reactions or possible dysfunction of the main organs are manifested. In other matters, as well as the reversibility of the consequences from the use of Atrovent and Ventolin.
Atrovent’s side effects are almost the same as that of Ventolin. They both have few side effects. This implies that the frequency of their manifestation is low, that is, the indicator of how many cases of manifestation of an undesirable effect from treatment is possible and registered is low. The undesirable effect on the body, the strength of the influence and the toxic effect of Ipratropium is similar to Ventolin.
My wife applied this inhaler daily. She felt better after started the application of this medicine.
My doctor prescribed me this inhaler to cope with my asthma. I am absolutely satisfied with the effect as my asthma attacks reduced in number. I hope this drug will be further effective in my individual case.